COLPOFIX® for the prevention and treatment of cervical lesions caused by the human papillomavirus (HPV)
Bucharest, Romania (Europe)
Contact: sales@gerovital-gh3.com
Ph: +40723141550 (whatsapp/viber/telegram)
COLPOFIX® IS AN INNOVATIVE VAGINAL SPRAY GEL
Colpofix® is a vaginal spray gel indicated for the
prevention and treatment of cervical lesions caused by the human papillomavirus
(HPV).
It has been a success in its country of origin, Italy, and is
already present in several other European markets.
Colpofix® is one of our most promising products and was
awarded by the Excellence in Pharma: Highly commended 2020 prize in the
Finished Formulation category at CPhI Worldwide 2020, the largest and most prestigious
pharmaceutical event in the world.
HPV is the most common sexually transmitted infection in the
world, and the most virulent genotypes may cause cervical lesions to develop,
which are implicated in cervical cancer.
The main components of Colpofix® are polycarbophil and
carboxymethyl beta-glucan. It has been evaluated through 4 studies involving
more than 2,000 patients, in which it demonstrated both clinical efficacy and a
very high safety profile.
Composition
and mode of action
COMPLEMENTARY
EFFECT OF ITS COMPONENTS
The
biofilm formed by polycarbophil allows for the bioadhesion of carboxymethyl beta-glucan
to the cervical tissue, ensuring its distribution and increasing the contact
time, which in turn allows for the prolonged action of its effects.
A)
Carboxymethyl beta-glucan
B)
Polycarbophil
CARBOXYMETHYL
BETA-GLUCAN
Contributes
to the maintenance and restoration of the vaginal microbiota through a specific
prebiotic effect: providing a specific source of energy for Lactobacillus sp.,
thereby promoting their growth and domination of the vaginal microenvironment.
POLYCARBOPHIL
In
association with mucin, it forms a mucoadhesive protective film, which remains
in situ for a prolonged period.
This
protective mucoadhesive film shields the vaginal mucosa from external microbial
agents, as well as supporting the maintenance and control of the physiological
conditions in the transformation zone of the cervical-vaginal mucosa through
moisturisation.
Colpofix®
can be used:
FOR
THE REGRESSION OF LOW-GRADE CERVICAL LESIONS
AS
A RECOVERY TREATMENT AFTER CERVICAL SURGERY ON HIGH-GRADE CERVICAL LESIONS
Colpofix® is an innovative vaginal spray gel. Its exclusive spray formulation allows for uniform and effective distribution of the gel on the cervico-vaginal mucosa, without associated spills.
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